A variation of the classic "brb", meant to imply that you will be back after answering nature's call.
Marcus221 says: brb bio

Legendsword says: #1 or #2???

Marcus221 says: we'll see! ;)
by josh_or_socko September 10, 2008
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Internet slang for "Be right back, biology break," in which "biology break" refers to going to the bathroom.
by eric osgood is a huge n00b August 11, 2008
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Used by gamers to let their party members know they are taking a small bathroom break.

Party members walk up to the boss room
The healer really has to pee
"Guys brb bio" - The Healer
"Ok np" - The tank
"What?" - The rogue
"She will be right back, bathroom break" - The Tank
"What's bio?" - The fighter
"It means Bathroom In and Out, and sometimes biology, because nature is calling" - The Tank
by razersnek February 5, 2023
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