Butthole Share definition Flag What your girlfriend, Madeline, is being whenever you try to be sweet and she calls you lame. Me: "Madeline, you're so beautiful!" Madeline: "You're so lame." This would make ber a butthole. Butthole by Atlas96 February 25, 2019 0 0 Get merch Get the Butthole mug. Buy Now — $32.95 See more merch