that's whats up good lookin out 

1. an expression of approval and thanks for a good deed, OR, 2. can be used in sarcasm to show disinterest in someone's actions or feelings

1. Miss Utility: "I'm not wearing any panties."
Tito: "That's whats up good lookin out!"
or
Danny: "I got laid off today. I need to look for a new job."
Tito: "That's whats up good lookin out?

that's whats up good lookin out by goose smacker March 1, 2009

knows whats up 

A descriptive measure of a woman's predisposition to engage in sexual activities.

AKA: Down to Fuck, Puts Out, Down with the D

Person A: Hey, you that chick over there?
Person B: Yeah, I bet she knows whats up.

knows whats up by Bed Knight October 3, 2009

show em whats up 

fight them

i'm gonna show em whats up

show em whats up by @astro_cat November 20, 2017

thats whats up 

Something bad that happens

Thats whats up when you mess with me

thats whats up by Dildo August 4, 2003

Whats Up With series

Running from 2015 - 2017, "Whats up with" was a YouTube series by Peter Knetter. First episode "What's Up With: Sonic and the Black Knight" first aired on Nov 23 2015. The series was where Peter (Peter Knetter) talks to cardboard characters.

Peter (2015-17)
Silver (2015-17)
Shadow (2015)
Sonis (2015-2016)
Chuckles (2015-2016)

Mario (2016)
Nick (2017) *as of "Whats Up With: Sonic's Schoolhouse"*

"Whats Up With series" a YouTube series that is no longer being filmed

Whats Up With series by aripods September 13, 2021

WHATS UP DOC 

WHEN YOUR HEAD IS BACK ON THE HEAD REST OF YOUR SEAT AS YOU ARE GETTING HEAD

I AM COMING HURRY UP SAY WHATS UP DOC

WHATS UP DOC by littlebitlight May 9, 2023

whats up brothers 

a way to greet someone in a funny or goofy way

whats up brothers

whats up brothers by imaslaywoman;) May 2, 2024