Yes in a down syndrome voice

When someone says yes but like they are missing chromosomes

"YEEEEEESSSSSSS"
"oh no hes doing yes in a down syndrome voice"

by WildWillez December 13, 2020

Down Syndrome Ass

A large and disproportionate butt

Yo Trayvon, have you seen Lynteria's ass lately. That girl is walking around with a down syndrome ass without even knowing it.

by White Boi Brain January 16, 2024

Deployment Driven Down Syndrome

A neurological disorder generally presenting itself in males aged 18-40 as a result of deploying to environments that are so hot the brain cooks inside of a helmet that is bombarded by high frequency radio waves and X-ray radiation while simultaneously trying to figure out exactly what the mission is. The people who are handicapped by this syndrome return noticably impaired in both mental and physical capabilities.

My uncle has Deployment Driven Down Syndrome (DDDS). He spent 9 months looking at the same patch of desert for 8 hours a day during OSS while running a backscatter.

by The Cap N' August 21, 2023

Phantom Down Syndrome

When somebody doesn’t have Down Syndrome but they look like they should

Bella Ramsey and Halle Bailey have Phantom Down Syndrome

by Sexier Boomhauer April 24, 2025

Dicked Down Syndrome

Temperamental shift in females caused by increased testosterone levels stemming from big dick driven polyamory and excessive sexual intercourse. Leads to a reduced ability to pair-bond and leads to a shift in sexual selection choices (from "preference seeking" to agreeableness and stability). Tell me that I'm fucking wrong though shit-brains.

Iam "Did we do one on Dicked Down Syndrome already?"

Hym "Hmm? No... I don't think so..."

Iam "Then how did predictive text know that 'ability to' would be followed by 'pair-bond'?"

Hym "Hahaha! Even the predictive text knows it's true!"

Iam "We must have used that line before..."

Hym "I'm surprised we haven't used 'big dick driven polyamory' until now. Seems like we've been sitting on that on for a while. Just like the $10 and hour whore! Bah dum tss! HAHAHAHAHAAAA!!"

Iam "I'm serious though. If only 3% of the population have 'dark triad traits' and we don't know why women are attracted to them; how for you account for the other 7-17% of men who are hyper-attractive to women?"

Hym "You account for it with big fat cocks. They're attracted to 'dtt' because sometimes people with 'dtt' have fat meaty dongers and your daughter loves it. Hahahaha!!!"

Iam "I mean isn't it strange that he never asks what the commonality is between the hyper-successful men with 'dtt' and those without?"

Hym "Remember how she started crying when we called her a $10 whore to her face? HAAAHAHAHAHAHAHAHAAAA!!!"

by Hym Iam April 13, 2022

Hand me downs syndrome

1) When a younger sibling feels entitled to everything their elder sibling owns.

1)Agh! My little sister stole my new Mac lipstick again! She's got total hand me downs syndrome!

by Ulessa April 20, 2017

down syndrome ass

"Down syndrome ass" is a colloquial term used to describe a buttocks that appears larger or differently shaped than typical. It's often characterized by a notable prominence or awkwardness in its form, resembling the appearance associated with Down syndrome, a genetic disorder. This term is not medically or scientifically recognized and can be considered offensive due to its derogatory nature.

"Yo, check out Shawty over there with that Down syndrome ass, it's like two basketballs stuffed in her jeans, no lie."

"Yeah, she got that Down syndrome ass, it's like she's carrying a whole extra load back there, making heads turn on the block."

Bro, her booty's like 'bam!' – Down syndrome ass, making the hood go wild, you feel me?"

by Brained February 7, 2024