(noun) a disease combining various STI's from numerous sex encounters and poor hygiene. Mostly snagly skunts catch this. There is no cure
by Cory n Jamez December 20, 2006
Get the herpaghonasiphilitis mug.A combination of the diseases Herpes, Ghonoria, and Siphilis.
I dated a dirty woman who had Herpaghonasiphilis.
by Derrik Abner June 13, 2008
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Herpaghonasiphilitus is a terrible disease that no man or woman should have to bear. It is a combination of the sexually transmitted diseases-herpes, ghonareah, siphulus, and hepatitis c. The disease causes the persons sexual organs to quickly and painfully rot away. Once it's rotted away the sex organs it moves on to the pancreas, the kidneys, and then before death the heart and brain. There is no known cute for this disease.
Blake: hey I think I got Herpaghonasiphilitus from that chick Sam.
Garrett: you're screwed man there ain't no cute for it.
Blake: totally worth it *dies*
Garrett: you're screwed man there ain't no cute for it.
Blake: totally worth it *dies*
by Cthulhu Windsloft Paper Master December 8, 2013
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