Piss in my pants. 

When something or someone is so annoying that they are as unpleasant as piss in your pants.

God, Becky is annoying with her yacking about the prom and her boyfriend..She's such a piss in my pants.

God this internet is so slow..its such a piss in my pants.

Piss in my pants. by Chip Shilpa August 6, 2011

you're the piss in my pants 

used to insult a close friend in a joking hilarious way
WARNING: only use around close friends

Jose: Jenn, you annoy me so much
Jonn: *Gasp*
Jose: In fact, you're the piss in my pants

you're the piss in my pants by lmaocity July 20, 2016