When a woman wears red panties for a night out by herself or with the "girls"and leaves her man at home, she's looking to get laid/have sex with someone else.
"I found nude pics on my boyfriend's IPhone from some nasty bitch, fuck it...I'm going tothe club. Where are my red panties?"
Person #1: Ya'll best be fixin' to get them fences up 'fore I get mind to tan your hide!
Person #2: I reckon you keep your panties on, darlin', or you gon' get madder than a wet hen!