weezo (derogatory) is a word used to exclaim distaste against someone, usually when they do something profoundly stupid or you just really hate someone
person 1: "hey guys check this out"
person 2: "nobody cares you fucking weezo"
person 1: "oh ok"
"Heybabe, you need to stop making these weezer references and this 'weezology'"
"Aw man, as they say, 'This Is Such A Pity' by Weezer!"
"Y'know what, I'm going to leave you if you keep doing this"
"Was that a reference to 'Getting Up And Leaving' by Weezer, where the lyrics state, 'Now I'm getting up and leaving'?"
Weekend spent doing nothing but forgetting your life is a constant waste so in order to forget about your personal problems and the past five days of torturous work you engage in numerous bad decisions. You forget what driving sober feels like and think condoms are the devil. Oh, and the occasional finger in the assmay be necessary to finish while drunk sexing.