1. Usually a very unpleasant girl with an unpleasant face. There's an odd chance of it being a pleasant girl, but still with a mildly unpleasant face.
2. A girl with an incredibly large nose
3. A try-hard-get-none hoe
4. A girl with acne and a lot of it
Guy1: That girl is such a hoe
Guy2: And look at her nose she's such a cassy!
Guy1: I'd do her with a bag over her head.