1 definition by alex neff

To be made a fool of; To make a fool of; To confound or prove wrong; embarrasing someone
also Total and undeniable dominance of a person, group of people or situation as to make them/it akin to ones bitch.
Dude! you just got Neffed up the A! or
You were really neffed when you walked in on your girlfriend cheating on you.
by alex neff December 7, 2007
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