1 definition by TweakOrBust

To not relax; to not chill; to mimic someone suffering from a unique combination of schizophrenia and terets, presenting a lack of logical thought upon speaking.
Don't tweak bro, relax.

I'm chill man, I never tweak on acid.

Relax for a second, or you might start to tweak.
by TweakOrBust December 4, 2017
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