1 definition by The_sp00k

A chronic illness, commonly brought on by drug use, which is often seen in men. The afflicted men will behave in unusual ways, such as saying embarrassing or unruly statements.

Severe cases of Scrote-Brain can lead the afflicted individual to display physical behavior beyond rational explanation, such as digging through trash, hoarding, terrorizing the general populace, etc.

Scrote-Brain is thought to be incurable. However, some studies have shown positive results with the afflicted simply choosing to improve their lives of their own volition. Due to this mechanism, the recovery rate is both exceedingly miniscule, and highly random.
"Did you see that guy licking the pavement behind the KFC? He looks like he's got severe Scrote-Brain."
by The_sp00k January 12, 2022
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