1 definition by TheJistOfIt

When, to settle a disagreement, two or more people see who can drink more alcohol (usually shots or beer). The person who stays the most sober the longest wins.
"Madison and I couldn't agree on when to go see the movie so we had a Mexican Drink Off."

"Tony and Luke had a Mexican Drink Off to see who got to ask that new foreign girl out."
by TheJistOfIt August 25, 2014
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