1 definition by Take that Jack

OB

Short for Oh Brother.

Usually said in conversation when wanting to express emotions of exasperation.

Liz Lemon (30 Rock): (Rolls eyes) "Ohh brother"

Weirdo: "OMG don't you dare put that on fb.. I look soooo fat! Delete it now! DELETE IT!"

Denise/Justine/Trish: "OB!"

by Take that Jack November 1, 2009