a condition relating to the excessive playing of the video game Madden NFL 200-whatever.
1. your hands are hurting excessivly because of overplaying.
2. you withdrawl from all your friends to play the game in your dark basement alone.
"Sorry I can't type. I've got Maddenitis."
"Hey, how about you call Chad to see if he wants to come to the movies with us?"
"Nah, he's got Maddenitis."