1 definition by Rube Sofer

Make a sissy

To take a piss. To take a leak. To urinate

From the series "Dead Like Me" the character Rube played by Mandy Patinkin uses the euphamism as a character trait.

George, hold on a minute. I have to make a sissy, then I want to talk to you.

by Rube Sofer April 5, 2010