Misanthrope or misanthropist.
A person who has a general dislike or distrust for the human race. Although they dislike the majority of the human race they can function considerably well in sexual and friendly relationships. They are often humored and disgusted by the human species. They are not often harsh or bitter people.
Misanthropes need people; without a steady supply, the misanthrope cannot fully apply his art.
Macabre is a term used to describe Gothic, dark and grim works of literature and art that usually have strong connections with death.
Tim Burton's work is macabre.