Unlike son of a bitch which is in reference to ones canine mother, son of a motherfucker is in reference to ones father that it is assumed was a motherfucker.
Can also be used as a curse when frustrated or infuriated by something.
Ask Doug?! Why, I wouldn't trust that son of a motherfucker as far as I could throw him.
What is wrong with this goddamn remote?! Son of a motherfucker!
After spilling your cereal all over the floor:
Oh, man. Son of a motherfucker! Shit!
1. A term used to describe someone that you hold in utter disregard or contempt.
2.Verbal slur meant to demean and emasculate a potential opponent in a street fight.
3. Term used to describe somebody that has ripped you off or offended you in any number of ways.
1. I hate that piece of shit cocksucker!
2. C'mon! You piece of shit cocksucker! Fuck you!
3. Nine hundred dollars?! That piece of shit cocksucker!