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Definitions by Mr. Wisdom

piece of shit cocksucker

1. A term used to describe someone that you hold in utter disregard or contempt.

2.Verbal slur meant to demean and emasculate a potential opponent in a street fight.

3. Term used to describe somebody that has ripped you off or offended you in any number of ways.
1. I hate that piece of shit cocksucker!

2. C'mon! You piece of shit cocksucker! Fuck you!

3. Nine hundred dollars?! That piece of shit cocksucker!

son of a motherfucker

Unlike son of a bitch which is in reference to ones canine mother, son of a motherfucker is in reference to ones father that it is assumed was a motherfucker.

Can also be used as a curse when frustrated or infuriated by something.
Ask Doug?! Why, I wouldn't trust that son of a motherfucker as far as I could throw him.

What is wrong with this goddamn remote?! Son of a motherfucker!

After spilling your cereal all over the floor:
Oh, man. Son of a motherfucker! Shit!