1 definition by Mean Girls

The main character from mean girls.
Also known to everyone else as a Bitch. They are usually blonde, and rude. They have what they like to call "friends" which are actually just "slaves" to her every need. Regina is very annoying and really stuck up. She will lie to your face, and talk behind your back. The usual name for a Regina George is Emma, Mackenzie, or Maddi but its best to stick with Regina.
Regina George: Where did you get your skirt it's so fetch!
Sally: My mom got it for me.
Regina George*walking away*: That was the ugliest skirt I've ever seen!!
by Mean Girls January 26, 2013
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