The act of a vampire trying to fit in with human society, such as drinking synthetic blood while being able to be around the human population. Refraining from feeding from humans while in social situations.
While at Fangtasia, Bill told Pam he hadn't been around much, as he had been mainstreaming. (characters from True Blood)
Slang for vampire blood; used on the show True Blood. Supposedly improves the health and libido of humans who consume it.
"Do doctors know that V-juice can do this?" (Sookie Stackhouse, from True Blood)