One who derives sexual pleasure from or seeks out relationships with individuals who have Down Syndrome as a result of an extra chromosome. There are no gender boundaries in a chromiesexual relationship, so if the individual in question has an interested Homie with an extra chromie, it's fair game.
"Jerry just came out yesterday."
"Jerry's gay?"
"Nah, he's chromiesexual. When he found out Jenny's got Trisomy 21, he about lost his mind."
"Jerry's gay?"
"Nah, he's chromiesexual. When he found out Jenny's got Trisomy 21, he about lost his mind."
by JamBamThankYouMa'am November 19, 2023