1 definition by HardenThicke

An erythema of the buttocks and upper inner thighs that resembles the red bottom of a baboon, commonly the result of systemic allergic contact dermatitis, or prolonged, rough, doggy-style banging.
1) My Baboon Syndrome was a result of my body's adverse reaction to the injection of ampicillin.

2) I pounded that bitch so hard, she gunna have Baboon Syndrome fo a week!
by HardenThicke December 3, 2009
Get the Baboon Syndrome mug.