1 definition by Darren Coleman

Term coined to describe the love/hate relationship between "Spike" and "Buffy", two characters played by James Marsters and Sarah Michelle Gellar in the hit series "Buffy The Vampire Slayer".

It is typically used as an adjective in normal conversation to exemplify traits exhibited in their on-screen relationship.
"Our relationship was very spuffy."
by Darren Coleman October 13, 2003