1 definition by ComedyCentralGuru

A show on Comedy Central about a queer Daniel Tosh who tries to make fun of other peoples videos, but ends up looking like a retard himself.

He usually sounds like he is on crack and looks like he just got D!ckslapped right before starting the show.
Tosh.O is totally the best show ever!
by ComedyCentralGuru July 21, 2010
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