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Definitions by 205K

brainqueef 

When you FUCK UP. Specifically due to the amount of drugs you consume. Instead of brainfart, its brainqueef because queefing is taking it to the next level. This word originated from 205k.
Gotdamn Janet brainqueefs all day cause of all the drugs she does.
brainqueef by 205K November 9, 2009