xantippe Share definition Flag A shrewish wife. From Xantippe, the wife of Socrates. e.g., Amazing how fast a new wife turns into a xantippe as soon as the honeymoon is over. xantippe by Joel D. Parker September 26, 2006 0 0 Get merch Get the xantippe mug. Buy Now — $32.95 See more merch