wyu2 Share definition Flag wyu2 is an abriviated form of 'what you up to?' W = what Y = you U = up 2 = to person1: wyu2 person2: not much, just surfing the web. wyu2 by dylan klebold August 13, 2007 0 0 Get merch Get the wyu2 mug. Buy Now — $32.95 See more merch
