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Meaning: What the fucks up?
Started from the Truth commercials that are against the tobacco companies.
Tobacco companies compared the addictivness of nicotine to jogging and m&m's. Whadafxup?
whadafxup by Alk3 Ownz U July 31, 2006
Related Words
1) Stands for what the fuck is up?

2) A commercial trying to inform people about "Big Tobacco's crazy ways and addictive products"
whudafxup with that!?

WOW, I love that whudafxup commercial!
whudafxup by bockz April 16, 2007

whuddafxup? 

Slang for "What The Fuck Is Up?"
But, it sounds cooler.
lolz.
Gina kissing a girl.
Mariah walks in.
Mariah- "whuddafxup? WHUDDAFXUP?!?!?!?!"
Gina- "I'm so sorry............."
whuddafxup? by MariahGina March 25, 2007
slang that is used to mean "what the fuck is up?"
is also an anti-tobacco ad capaignhttp://www.whudafxup.com/
shelly.. whudafxup w/that?
whudafxup by dfhdfh September 3, 2008
Idiotic anti-tobacco propaganda which uses scare tactics and idiot comparisons to spread irrational fears about tobacco. Hosted by some jackass who looks like he showers once a year and aspires to look as much like an insect as possible with his clothes and glasses.
went to a gun store to ask for light bullets, whadafxup?
whadafxup by robbles August 23, 2007
The lamest, stupidest, gayest commercials about cigarettes.
Whudafxup is a gay commercial.
whudafxup by BigZaccyStyle September 15, 2006