Top Definition
It's like saying "nizzle" where nizzle represents nigga, except "wootizzle" represents woot.

See also "How Snoop Dogg would say Woot."
Person 1: I just KO'ed Mike Tyson in Mike Tyson's Punch Out!
Person 2: WOOTIZZLE!
by tjscott87 August 24, 2007

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