look up any word, like cunt:
 
1.
what is up, a greeting
E:Aye gurl, whuddup?
A: Oh you know, same old same old.
E: Niiiice, niiiice, i gots to jaam.
A: Igght, peeace.
by elisaaaa October 25, 2007
 
2.
A lame spelling of the common "wuddup." However, it is not used as a greeting in most cases. It is commonly used as in introduction on meaningless facebook updates in times of distress when the user wants to appear cool or hip in nature, usually to much failure and pity.
Jim: "Whuddup new shoes!"
Carl: "wow...what do I even say to this?"
by milkmanmaxxie February 08, 2011