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what's your poison 

1. A query as to one's preference, specifically in regards to consummable goods
2. a query as to one's preference in alcoholic beverage or drugs
3. a question of one's preference in women
1. Alfred: What's your poison?
Rudyard: Give me a slice of pepperoni, beyotch!

2. Alfred: What's your poison?
Rudyard: Give me some mother fuckin' crack!

3. Alfred: What's your posion?
Rudyard: I likes me the big-titty bitches yo!
Alfred: Word!

what's your poison 

What are you drinking? Usually in terms of alcohol
"Whats ya poison?"
"Tequila slammer"

What's Your Poison? 

An awesome podcast that talks about anything that makes people uncomfortable. Like awkward sex, brutal crimes, and anything taboo, all while drinking some sort of appropriate alcohol. Booze & Taboos.
-Have you heard the new episode of 'What's Your Poison?'
-No, why?
-She had to explain fisting to her grandmother!
What's Your Poison? by Moxology September 23, 2019

What's your poison, folks? 

used to ask someone what they would like to drink.
The bartender raised an eyebrow at the group and asked with a smirk, "What's your poison, folks? Whiskey, beer, or something more exotic?"

whats your poison? 

usually said by sleazy guys in bars as a way of asking to buy you a drink
"hey...What's Your Poison"
"baileys now feck off"
whats your poison? by Beaky February 29, 2004
It is said of the situation where a person has the bad luck to make contact with his testicles against an undefined surface or object, intentioned or not.
Given the nature of the word, it is more appropriate to design cases where the interaction is made with a moving object, for example, a ball.
Although it is extremely painful for the victim, it tends to be considerably funny to people who witness it.
Today in the baseball game the pitcher took a nutshot; the baseball hit him in the nuts.

Man, I just watched the funniest nutshot video ever.
Nutshot by Uberflaven March 1, 2009
Word of the Day on June 26, 2026