A 7-Up TV advertisement from 1999-2005, which featured comedian Orlando Jones wearing a green t-shirt that said "MAKE 7" on the front of it, and "UP YOURS!" on the back of it. Jones would then walk around and tell people to "Make 7-Up Yours!", where he would get responses like an angry insulted guy yelling "Same to you!"
This advertisement actually became so popular that shirts similar to the one Jones wore became available for sale through many gag-gift catalogues, record/CD stores, and Media Play entertainment centers.
ORLANDO JONES: I'm the guy who makes 7-Up, and I also write the advertising. I just came up with a great new slogan - "Make 7-Up Yours!" *points at front of shirt* "Make 7", *points at back of shirt* "Up Yours!"...
Up yours nigger is a line that was said by the greatest grandma in history from the movie Blazing Saddles
Sheriff: Good morning ma'am ain't it a lovely morning
Greatest grandma: Up yours nigger {walks away salty}
~later~
Greatest grandma: good evening sheriff! Sorry about the up yours nigger. I hope this apple pie is a small thank you for your ingenuity ang courage for beating that horrible Mongo (PS mongo is a awesome character to and remember Mongo straight)
Sheriff: thank you good night
Greatest grandma: of course you'll have the good taste not to mention that I spoke to you
Sheriff: of course good night
The most INFAMOUS definition of the commonly used word up (↑).
Means shove it up your ass or worse, using only innocent words - it is EQUIVALENT to fuck you!
If you are not using this as an insult, you are a stupid fucking idiot who cannot even count! Hahahahahaha!
Julia, unfortunately explained, "I am sorry, but you have not been selected to the Elite Community. I hope you can try next year..."
Yaha shouted, "UP YOURS! YOU MUSTHERFUCKING ILLEGITIMATE COCKWANKING HEAP OF ABOMINABLE DOGSHIT - YOUR WORDS ARE FUCKING STUPID"