unspool

To lose one's mind as a result of a major emotional shock, from the pilot episode of the television series Wonderfalls:

(Jaye discovers that her sister Sharon is a lesbian)

Jaye: Does Mom know?

Sharon: She would unspool!

Jaye: Can I tell her?

by Mike May 2, 2006

unspooling

A word used by 4chan losers to describe someone they believe is "going crazy".

LOL I caught you online on the forums at 3 AM UR unspooling

by Downvoting Victim September 11, 2020