Top Definition
(N.) Homer Simpson's (II) Catch phrase in the short-lived Fox Dramedy, "Police Cops." Originally, a suave, stereotypical Policeman, Homer Simpson (II) was retooled into a fat, bumbling, Chris-Farley-esque doofus, who's catchphrase was always "Uh-Oh-Spaghetti-O's!" which was taken from the pasta of the same name.
Homer: "I just helped out in the Toys-for-Guns program."
Chief: "Homer! It's Guns-For-Toys!"
Homer: "Uh-oh spaghetti-o's"
by G-Union November 25, 2003
An expression of regret over a goof: oops. From a 1970s TV commercial for Franco-American SpaghettiOs, a canned pasta dinner sometimes with meatballs or sliced frankfurters. Another Homer Simpson quote.
Uh-oh, Spaghettios!
by LudwigVan November 13, 2003
please refer to oh shit
cop: "Sir are there any drugs or any weapons ion your vehicle that I should know about?"
me: "No sir!"
cop: "HOLY SHIT there is over 10 punds of weed in your trunk"
me: "uh-oh spaghetti-o's!!!"
by MetalHead November 23, 2004
usually when something goes wrong or you just started having drunken sex to realise its your sister!
"i think ive caught my scrote in my zipper " "uh oh spaghetti o's"!
by matt and the winz March 16, 2004
"oh shit"
term borrowed from the late 1970's-ish commercial jingle for franco-american's spaghetti-o's
*camera shows to hippies smoking weed*
dude. we just smoked 2 bowls. i am starving. what do we have to eat?
*cue annoying jingle*
uh-oh, spaghetti-o's
*camera shows 2 confused gentlemen having just heard said jingle who now smile, realizing they have canned "spaghetti" to eat*
*and fade to black*
by mr pink November 18, 2004
1. oh, shit
2. oops (sarcastically)
"Hey! you just made me drop all of my books!"
"uh-oh spaghetti-o's! *runs away laughing*"
by goog November 11, 2003
1. A phrase to describe a situation gone awry.

2. A phrase that is used to bring offense to a woman who just had a miscarriage.

3. A phrase associated with a canned soup tasting of old ketchup and cheap noodles.
"Did you just bust in my vag?!?" "Uh oh, Spaghettio's!"

"Ever since my miscarriage, I've never been the same." "Uh oh, Spaghettio's!"

"Tastes Like Ass for 100. This phrase was associated with a Campbell's soup product." "What is uh oh spaghettio's?"
by Bilbo B4ggins September 23, 2009
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