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This phrase has a double meaning:

1) The hangover is so bad that it's a two-story hangover

2) This is when you wake up after a night of drinking and partying and you have two stories from the night before. One story is about getting hammered and having a great time. The other story is about having sex with some nasty chick that you don't even know....damn
ex. Dude, I've got a two-story hangover after that kegger last night!!

ex. I had fun but I had a two-story hangover in the morning.
by B-Razzy May 08, 2005
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