Top Definition
Exactly the same as a recluse which is

1. a person who lives in seclusion or apart from society, often for religious meditation, and or because they are on a sick one spun out on crystal meth.

2. shut off or apart from the world; living in seclusion, often for religious reasons, or because they are totally resigned to being a tweeker and enjoying it.

3. characterized by seclusion; solitary; continually consuming crystal meth which cancels out the loneliness.
I don't know if Tom is still alive, he is such a tweekcluse these days and never leaves the house!

Its a good thing Natalie is a tweekcluse, that way she is always available to fix our wagon!
by Bedragglementation June 05, 2009

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