Exactly the same as a recluse
1. a person who lives in seclusion or apart from society, often for religious meditation, and or because they are on a sick one spun out on crystal meth
2. shut off or apart from the world; living in seclusion, often for religious reasons, or because they are totally resigned to being a tweeker
and enjoying it.
3. characterized by seclusion; solitary; continually consuming crystal meth which cancels out the loneliness.
I don't know if Tom is still alive, he is such a tweekcluse these days and never leaves the house!
Its a good thing Natalie is a tweekcluse, that way she is always available to fix our wagon!