An chronic disorder, usually the result of having a vagina. Symptoms include a heightened sense of drama- especially when none exists, bitchiness, poor sense of direction, failure to understand simple instructions like "make me a sandwich, now!", and neediness. People with the disorder tend to cry, and make stories up.

Deep penetration can sometimes alleviate the symptoms for a while, but tend to result in addiction, and "emotional dependance".

Can happen to especially whiney guys.
Girl- So I was talking to my friend the other day, and you have to understand, I was on my rag at the time and so I was feeling insecure, and she made a comment that I sorta thought might mean she thought I was fat and.....

Guy- Well this sounds like a classic case of twat syndrome to me. Just shut up!

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Bitch- Why do you have to be so insensitive all the time? Can't you respect me for once?

Guy- I do respect you, but you have twat syndrome and can't tell. Haven't we talked about this before?
by Fried Donut February 12, 2008
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A term used to describe a complete pain in the arse who thinks they have ADHD, but in fact have been a little twat from birth. This condition is usually only known by their mother.
"Mum, I think I have ADHD. No you don't son, you have little twat syndrome. You've had it since you were born."
by Jester1988 December 5, 2016
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Various foreign substances the create a powerful, often toxic secretion from the vagina. Can cause serious chemical burns when in contact with fingers, mouth, tongue or penis for prolonged exposure . In some cases, it has even eaten through the subjects panties, jeans and boyfriends car seat. Extreme caution should be taken, and in most cases the subjects must be incinerated.

In rare cases, it also accompanies ESD (Excessive Saliva Disorder)
Yuck! Tasha has TTS!!
by SquishyConey September 3, 2003
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someone who's vagina has been smashed so many times it begins to look like a nasty ass waffle
she had been screwed by so many football teams it looks like she has twat waffle syndrome
by useless youth August 7, 2009
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