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1.
When a female prevents another female from scoring with a man.
Emma is such a twat block. Danny and I were supposed to be on a date, but she showed up and they talked the entire time!
by cindy yetti March 11, 2008
 
2.
when a female is deterred from pursuing a partner by unwanted participant. NOT when a girl cockblocks a guy.
Laura: "hey brend.."
Mike: "HEY BRENDAN! GET OVER HERE!"
Brendan: "Oh, hey Mike what's up!"
*Mike carries on a dead end conversation with Brendan before he takes his muffins and leaves*
Laura: "Hey asshat, why did you twatblock me?!"
by sarahtheresahhhh November 02, 2008
 
3.
When somebody directly interferes with a girl's ability to have sex with a guy. It's essentially the female version of a cock block.
Sarah: I can't believe I just got twat blocked by my friend. I'm so pissed!

Hannah: Some friend!
by Michael Hammond May 03, 2013
 
4.
(v 1) When a female interferes* with someone, typically a male who is getting acquainted with, conversing with, or hooking up with a member of the opposite sex.
(v 2) any action that impedes or stalls another's "game", "mack", or "pimp manuver"

(n) any female one who prevents another person from getting to know someone.

*Often intentionally
(1) Jim was talking to Lisa. That is until Jims little sister twat blocked him when she asked why he needed two girlfriends.
(2) My ex-wife twat blocks me every chance she gets. I hate her.
by Solar1 April 06, 2009
 
5.
The act by a FEMALE to prevent a male from talking to a woman, most likely by
1) a friend of the woman the male is persuing
2) a female that likes the male that is clearly interested in the other female

(a FEMALE cockblock)
1)
Female 1 to group of girlfiends - "Like Oh-em-jee! Mary is totally getting hit on by that jerk David! she SO needs a twatblock!

Group of girls - "Like TOTALLY!"
----
2)
Male 1- "Damn Mike, you just totally got twatblocked by that chick"
Male 2 - "Yeah shes way under my standards, she just gets mad because I talk to chicks hotter than her."
by Mike Delicious July 16, 2006
 
6.
Twat being another word to describe the vagina, someone who twat blocks or is a twat blocker is a female who gets in the way of another female friend and a male.
Damn it Tina just because Jake broke up with you doesn't mean you have to twat block me now!
by Shaqo_Wyn April 10, 2010
 
7.
when a woman cock blocks another woman. TWAT BLOCK.
GIRL - HEY WANT TO GO TO MY HOUSE TONIGHT?
BOY- SURE WANNA GO WRITE NOW?
GIRLS FRIEND- SORRY WE GOT TO GO WALK MY DOG.
BOY- OK THEN BYE.

TWAT BLOCK
by TRIXSTER45 December 07, 2010