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The condition of having multiple serious psychological disorders. (EX- Paranoid schizophrenia, multiple personality disorder, anti-social disorder) People with this condition often times are unable to function properly in society or hold normal conversations with people.
He is so Tref that he needs to go to the hospital and be checked out
tref by 102SPT November 19, 2006
Related Words

trefeloquin

Adjective describing something that is shapely, cute, and easily forgiven.
That red bellied penguin is so trefeloquin, I just can't help but forgive him for eating my wife.
trefeloquin by Daniel November 14, 2004

Ruivers Treffe 

An prestigious annual soccer tournament. It's is held in the town of Reuver which lies in The Netherlands. People from the whole region come to this tournament.
''Hey how was this years Ruivers Treffe?''
''It was great, though I was send of with a red card''
''Oh, Why?''
''Because I scolded at the referee''
Ruivers Treffe by DutchPascal April 17, 2009

trefilific 

trefilific is a pp head
trefilific by thatbishfig December 13, 2020

The trefo 

A dope ass city located in North Carolina that has the the third highest crime rate but is the fourth biggest city.
"My life, my city, the only life that I know I said tre fo"

"Bruh are you singin dat trefo anthem"

"Hell yeah because I love the trefo"
The trefo by cash.money November 5, 2011
A combination of the words "true" and "deff". It is used as a substition for either; or to agree with a previously spoken statement.
Treff by ilannnnaaaa March 29, 2009