Noun. Slang: When a male friend is acting in a feminine nature, or a female friend is acting to masculine.
Friend 1(male): Sorry dude. I can't meet you up yet. I have to buy some new clothe for tonight. Then get my haircut and meet my gf. I'll meet you up in a couple of hours.
Friend 2(male): Fool! You don't need to buy a new dress. Quit being a trannie!