Top Definition
1. Caused when the female breasts interfere with an activity or a goal. 2. In pocket billiards, when the object ball strikes the corner of the felt by the pocket instead of going into the pocket.
1. "I was driving down the road, when I saw this girl on the side of the road, wich caused tittiference and I rear-ended the car in front of me."

2. "That ball would have gone in, if it weren't for the tittiference.
by toastido August 27, 2007
6 Words related to tittiference

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