8
Southern Tenant Farmers' Union (STFU): Large labor union, formed in Arkansas in 1934, which lobbied the federal government for better New Deal reforms. Dissolved in 1960. Commonly causes mirth among US History students who are aware of the acronym's double meaning.
Teacher: Joey will you please tell the class about the STFU?

Class: Hahahahahahahahaha
by jer February 24, 2005
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9
The stupid bitch wouldn't STFU so I back handed her one.
by Sean October 25, 2003
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10
online text-speak for "shut the fuck up".
Perez Hilton needs to stfu immediately.
by tip123456 June 25, 2009
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11
Shut the fuck up. It's simple. When you are annoyed with someone who won't stop ranting on instant messaging, you type "stfu!!" But be sure to limit yourslef to two exclamation points, though, because three will look too angry. You could also type two exclamation points and then a "1". Like this: stfu!!1. This way, the third exclamation point is there, but only in spirit. This puts a little extra anger, but not so enough to make the other person angry at you. :)
~On instant messaging~

like_totally_cheergrl07: like omg omg omg we like totally had so much crap to do today in like science because the teacher is like so bitchy and she doesn't get that I have a life! I mean COME. ON. Wtf???!!!
xXxmy_heart_bleeds_blackxXx: stfu!!1
by Cexy October 13, 2007
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12
One of the few Oriental saints, recognized by the Catholic Church. He watches over some of the most annoying miscreants on mother earth, they are also known as "the never ending talkers" You may also know him as "SHUT THE FUCK UP"
One of our co-workers never did know quite when to shut his mouth, so we always tried to call on St Fu to intervene before we beat him like a red headed step child.
by cobraglf October 01, 2007
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13
Shut-the-fuck-up: a term used when a normal request for someone to be quiet seems to fall on deaf ears; may be used in either a normal or assertive tone of voice.
Honey, would you be terribly offended if I asked you to please STFU for five minutes?
by Monkster1 June 24, 2010
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14
a widely-used acronym for "shut the fuck up"
Have a nice cold glass of shut the fuck up!
by Phishr July 20, 2005
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