to make someone's flesh crawl and make someone's skin crawl to cause someone's skin to feel funny or get goose pimples through fright.
Just to hear the story of the killings made my flesh crawl. The horror movie made our skin crawl. She brings a touch of bland dignity to even the most skin-crawlingly repulsive public spectacle.
From the popular Linkin Park song. You use this when somebody is being an angsty bitch and generally whining about their lives and how they have it so much worse than you. See angst
Although the previous definitions may be right. The true meaning of the words comes from the feeling you get when your high on heroine and you feel as though you actually crawling in your on skin and your skin is moving and trying to come apart.