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The act of removing a sister from your life, either physically or metaphorically. First used in the Simpsons episode "My Sister, My Sitter".
Simpson? Look, we've already been down there tonight for a sisterectomy, a case of severe butt rot, and a leprechaun fight. How dumb do you think we are?
by ubersmith May 17, 2016
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2
When a man with an African-American wife gets a divorce.
When Whitney filed for divorce, Bobby got a sisterectomy.
by joliet_jake1 February 13, 2007
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