Top Definition
When one becomes so full of shame/embarrassed that they are driven to fake sick or bothered as to avoid interaction with any human being or other creature.
Person 1- Dude, why'd you call in sick? You were fine yesterday...
Person 2- Ahh, last night was horrible! Puking on the hot coworker chick I was about to bang? I've got the shameflu...
by caiteelinn April 07, 2010

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