Slang for Methylenedioxyamphetamine or MDA, a psychedelic stimulant that can be classified as both a phenethylamine and an amphetamine. This term is popular among fans of jam bands and probably originated somewhere within the psychedelic music scene. The term is also used to distinguish powdered MDA from powdered MDMA, often referred to as "molly."
Head A: I ran into some righteous Sassafras at Rothbury, the campgrounds were full of it!
(n)--although the denotation specifies this as a tree, many have come to associate the connotation of "sassafras" with a term defining heavy amounts of sarcasm. Drawn from the root word, "sass," sassafras can be synonymical with sardonicism, facetiousness, witticism, or any other form of smarmy behavior.
Brandon could not take Spencer's unusual amount of sassafras, so he falcon punched her in the face. Twice.
If you don't quit that sassafras of yours, I will waslap you in the face. Again.