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1.
Used for "girl" or when attempting to seem and/or type "ghetto". Occasionally used as an acronym.
Susan "Today I was really depressed"
Tammy "Quirl you don't even know what depressed is, you better stop talking like that before I quirl you up"
by rilayy November 05, 2011
10 7
 
2.
A cigarette.
Used in the old west.
The haze mixed with the tabacco smoke from a dozen quirlies to turn the air a permanant grayish-blue.
by Daisy May 18, 2005
7 7