Top Definition
A condition which afflicts straight men (and possibly lesbian women) which impairs their ability to use sound judgment and common sense. Most often brought about by recent contact with vagina and/or the future potential of vaginal contact. Destroys interpersonal relationships, mental and emotional health and possibly small animals. First appeared in Greek mythology. Odysseus famously resisted pussy blindness by having his boat's crew tie him to the mast of his ship.
Dude 1: Man, B's been MIA since he's been hit by that pussy blindness!

Dude 2: Yeah, it's like he's forgotten that he has friends or family!
by ELesque March 10, 2010
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