A mixture of poop and puke. It can emit from either the throat or the anus and is equally surprising either way. Projectile pupeing has been observed in highly intoxicated individuals.
Did you see John just pupe all over himself? I ain't cleaning that sh!t up!
by Bob "the dream" Oregano March 28, 2005
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that poop you take that also makes you sick and shivery. you're on the toilet crapping when you suddenly feel nauseous. pupe is a mix of the words poop and puke.
oh no, i think i'm going to have a sweaty shivery pupe again... third time today
by aislinntheace April 8, 2009
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The intense expulsion of the contents of one's stomach and intestines by simultaneously puking and pooping actions. The regurgitating portion usually occurs through the mouth and sometimes the nose, while excrement exits out of the anus. It is usually the result of a night of binge drinking which eventually leads to loss of all bowel and esophagus control.
Mike: "Dude, so Dan ended last week's formal party by puping into a toilet while his date held his hand. He then proceeded to pass out on a bare mattress with a teddy bear on one hand, while his other hand flipped the finger."
Ray: "WagoooooooooooooOOOOOOOOOOOOoooo!!!"
Joe: "Yeah, well Sal took so many Irish Car Bombs at The Ruck last night that he passed in the shower puping. The water was of course running."
by RaymondJT August 13, 2010
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n. A pubic toupee, or hairpiece.

alt. sp. Poupee.

See also "merkin."
Evangeline wore a pupee to cover up her herpes.
by merkinator March 27, 2008
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The vomit that can only occur after a dog has eaten its own, or another animals, feces. It is a dazzling mixture of vomit and feces that causes a chain reaction of gagging and/or vomiting, making it very difficult to clean up.
"Dude, your dog just puped on the floor."
or "who's gonna clean up the pupe, because I can't stop gagging"
by A Ling January 16, 2010
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Pupe is when someone has such severe diarrhea that they basically just throw up out the poop hole instead of a puke out of the mouth when sick. Pupe is sometimes also known as throwing rooster tails, or blowing up the toilet.
Guy One: I thought Johnny was going to puke, but no! He dropped trow and puped on Shirley's lawn.
Guy Two: Wow, on the lawn? I guess it's kind of tough to hold back a fine pupe of the highest caliber after a good night of partying.
Guy One: Indeed it is good sir, indeed it is.
Guy Three: My Grand dad had to pupe once at a family reunion. He said something about never trusting a fart after 50.
Shirley: Get off my lawn, and hose off that pupe!
by HighlyMedicated September 8, 2014
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